You can place it as far away as you want as long as you size the pipe correctly.
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Hazen-Williams Water Flow Formula: Head Loss, Data, Charts & Calculator
Friction head loss (<i>ft<sub>H2O</sub> per 100 ft pipe</i>) in water pipes can be estimated with the empirical Hazen-Williams equation.www.engineeringtoolbox.com
For heating or cooling, there might be some heating or cooling losses at longer distances if the pipe is exposed to temperatures that are significantly different from the water temperature.
For example, if you are chilling the water and the pipes run across 200 feet of hot ground, the water will pick up some heat.
If you bury the pipe, the losses will be reduced.
You can use insulation on the pipes if you think that it will help reduce heating or cooling losses.
This is all going above my head.
Do you know what the math will look like for the chiller if it has a 2" Dedicated Return to the pool about 50' away? For what it's worth, we used sweep 90's (maybe about 4-5). There is a slight incline from the pad to the pool, but nothing crazy. Maybe a few feet max.