It would definitely be in your best interest to drain and get those uprights plumb. The force of water pushing against the wall will always seek out the weakest point. Drain and double check to make sure the bottom rail is perfectly circular before re-installing the liner and get all the uprights plumb and get the top rails all on. Then re-hang the liner and fill. Better to fix it right before cutting thr the liner.
Also just an observation but the bolts for the stainless access panel should be hidden behind the uprights. Not that it hurts anything the way you've got it now. It's mainly cosmetic to hide them.
24'x52" Artesian w/ Portifino liner - Hayward 1hp powerflo matrix w/24" sand filter - AquaTrol RJ SWG. Solar heating to come. -